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William Tyler

William Tyler

William.Tyler@asu.edu

Adjunct Faculty
Sols Administration & Faculty

Bio

PROFESSIONAL EMPLOYMENT

Assistant Professor of Neurobiology and Bioimaging 08/2006 to present

Arizona State University

EDUCATION/TRAINING

Postdoctoral Fellowship 01/2003 to 08/2006
Harvard University, Department of Molecular and Cellular Biology
Investigations: Activity-dependent Refinement of Neural Circuits in the Mammalian Olfactory System
Advisor Venkatesh N. Murthy, Ph.D.

Doctorate of Philosophy 01/2003
University of Alabama at Birmingham, Psychology/Behavioral Neuroscience
Dissertation Title Brain-Derived Neurotrophic Factor-Induced Plasticity of Both the Presynaptic and Postsynaptic Compartments of Hippocampal Excitatory Synapses.
Mentor Lucas D. Pozzo-Miller, Ph.D.

Bachelor of Science 08/1998
University of Alabama at Birmingham

Courses

Fall 2010

Courses Taught This Semester
Course Number Course Title
BIO 189 Life Sciences Career Paths
BIO 467 Neurobiology
BIO 499 Individualized Instruction
BIO 598 Special Topics
BME 598 Special Topics
MCB 555 Adv Molecular/Cell Biol I

Fall 2009

Courses Taught This Semester
Course Number Course Title
BIO 467 Neurobiology
BIO 598 Special Topics
BME 598 Special Topics
KIN 598 Special Topics
MAT 598 Special Topics
MCB 555 Adv Molecular/Cell Biol I
MCB 598 Special Topics
PSY 598 Special Topics
SHS 598 Special Topics

Spring 2009

Courses Taught This Semester
Course Number Course Title
BIO 360 Animal Physiology
BIO 361 Animal Physiology Laboratory

Fall 2008

Courses Taught This Semester
Course Number Course Title
BIO 467 Neurobiology
BIO 591 Seminar

Fall 2007

Courses Taught This Semester
Course Number Course Title
BIO 467 Neurobiology
BIO 494 Special Topics
BIO 591 Seminar

Publications and Other Intellectual ContributionsGoogle Scholar

  1. Tyler, W.J.. Ultrasound for Neuromodulation? A Continuum Mechanics Hypothesis. Neuroscienist (2010).

  2. Tyler, W.J., Y. Tufail, and S. Pati. Noninvasive functional neurosurgery using ultrasound.. Nature Reviews Neurology (2010).

  3. Baluch, D.P., J. Georges, P. Deviche, W.J Tyler. Estrogen acts through GPR-30 receptors to rapidly increase neurotransmitter release from hippocampal excitatory synapses. Society for Neuroscience Abstracts, 523.3. (2009).

  4. M.L. Tauchmann, Z. Gilbert, K. Cruz, W.J. Tyler. Sensory input gain is mediated by the context of associative learning at primary olfactory synapses. Society for Neuroscience Abstracts, 257.3 (2009).

  5. Rincon, L., Y. Tufail, G.E. Jabbour, S.I. Helms Tillery, W.J. Tyler. Channelrhodopsin-2 expressing neurons stimulated with blue organic LEDs. Biomedical Engineering Society Abstracts, PS 8B-170 (2009).

  6. Rincon, L., Y. Tufail, G.E. Jabbour, S.I. Helms Tillery, W.J. Tyler. Stimulation of channelrhodopsin-2 expressing neurons using organic LEDs.. Society for Neuroscience Abstracts, 770.14 (2009).

  7. Tufail, Y., A. Matyushov, N. Baldwin, M.L. Tauchmann, J. Georges, A. Yoshihiro, S.I. Helms-Tillery, W.J. Tyler. Remote stimulation of intact brain circuits with transcranial pulsed ultrasound.. Society for Neuroscience Abstracts, 105.1 (2009).

  8. Song, H, W. Kong, N. Weatherspoon, G. Qin, W. Tyler, J. Turk, R. Curtis III, Y. Shi. Modulation of the regulatory activity of bacterial two-component Regulatory Systems by SlyA.. Journal of Biological Chemistry (2008).

  9. Tyler, W. J., Y. Tufail, M. Finsterwald, M.L. Tauchmann, E.J. Olsen, C. Majestic. Remote excitation of neuronal circuits using low-intensity, low-frequency ultrasound. PLoS One (2008).

  10. William Tyler, Gabor Petzold, Pal Sumon, Venkatesh Murthy. Experience-dependent modification of sensory synapses in the olfactory bulb. Journal of Neuroscience (2007).

  11. William Tyler, X-l Zhang, K Hartman, J Winterer, W Muller, P Stanton, L Pozzo-Miller. BDNF increases release probability and the size of a rapidly recycling vesicle pool within hippocampal excitatory synapses. Journal of Physiology (2006).

  12. Z Li, J Burrone, William Tyler, K Hartman, D Albeanu, V Murthy. Synaptic vesicle Recycling studied in transgenic mice expressing synaptopHluorin. Proceedings of the National Academy of Sciences (2005).

  13. William Tyler, V Murthy. Synaptic vesicles. Current Biology (2004).

  14. William Tyler, L Pozzo-Miller. Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 pyramidal neurones. Journal of Physiology (London) (2003).

  15. William Tyler, M Alonso, C Bramham, L Pozzo-Miller. From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learning and Memory (2002).

  16. William Tyler, S Perrett, L Pozzo-Miller. The role of neurotrophins in neurotransmitter release. Neuroscientist (2002).

  17. J Cox, William Tyler, A Randich, G Kelm, S Meller. Celiac vagatomy reduces suppression of feeding by jejunal fatty acid infusions. Neuroreport (2001).

  18. N Filippova, A Sedelnikova, William Tyler, T Whitworth, H Fortinberry, D Weiss. Recombinant GABAc receptors expressed in rat hippocampal neurons after infection with an adenovirus containing the human ?1 subunit. Journal of Physiology (London) (2001).

  19. N Tartaglia, J Du, William Tyler, E Neale, L Pozzo-Miller, B Lu. Protein synthesis-dependent and -independent regulation of hippocampal synapses by brain-derived neurotrophic factor. Journal of Biological Chemistry (2001).

  20. William Tyler, L Pozzo-Miller. BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. Journal of Neuroscience (2001).

  21. A Randich, William Tyler, J Cox, S Meller, G Kelm, S Bharaj. Responses of celiac and cervical vagal afferents to infusions of lipids in the jejunum or ileum of the rat. American Journal of Physiology (2000).

  22. J Cox, William Tyler, A Randich, G Kelm, S Bharaj, R Jandacek, S Meller. Suppression of food Intake, body weight, and body fat by jejunal fatty acid infusions. American Journal of Physiology (2000).

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Presentations

  1. Tyler, W.J. Pulsed Ultrasound for Noninvasive Neural Interfaces. DARPA Novel Neural Interface Workshop. (Jan 2010).
  2. Tyler, W.J. Ultrasonic Neuromodulation: Noninvasive Remote Control of Intact Brain Circuits using Pulsed Ultrasound. Neural Restoration Workshop, Sandia National Laboratories. (Nov 2009).
  3. Tyler, W.J. Chasing Quanta and Building a Neurotechnology Company in Tough Economic Times. M.I.T. Neurotechnology Ventures. (Nov 2009).
  4. Tyler, W.J. Remote Stimulation of Neuronal Circuits using Pulsed Ultrasound. Translational Genomics/Barrow Neurological Institute/St. Joseph's Hospital. (Oct 2009).
  5. Tyler, W. J. Remote Excitation of Neuronal Activity using Pulsed Ultrasound. The Physiological Society Meeting. (Jul 2009).
  6. Tyler, W.J. Remote Stimulation of Neuronal Circuits using Pulsed Ultrasound. Department of Physiology Colloquim Series, University College of London. (Jul 2009).
  7. Tyler, W. J. Future Neurotechnologies. Neurotechnology Industry Organization Partnering Conference. (Apr 2009).
  8. Tyler, William BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. Annual Retreat.
  9. Tyler, William Optical analysis of neurotransmitter release from individual hippocampal presynaptic nerve terminals following BDNF treatment. Annual Retreat.

Research Activity Research Awards

  1. Tyler,William James * . The Development of Pulsed Ultrasound for Noninvasive Neural Interfaces. DOD-DARPA (6/16/2010 - 6/15/2011).
  2. Smith,Brian * Tyler,William James . Remote Control of Intact Mammalian Brain Circuits Using Pulsed Ultrasound. DOD-ARMY-ARO (9/1/2009 - 8/31/2012).
  3. Smith,Brian * Tyler,William James . Prairie Technologies 2-Photon Microscope - ARRA AWARD. HHS-NIH-NCRR (5/1/2009 - 4/30/2010).
  4. Tyler,William James * . Neurovisions: Teaching Neuroscience with Neuroimaging Data. Science Approach (2/20/2009 - 12/31/2009).
  5. Bimonte-Nelson,Heather * Tyler,William James . Ovarian Hormone Loss and the Aging Brain: An Analysis of Hippocmapal Structure and Function. SUN HEALTH RESEARCH INST (7/1/2007 - 6/30/2008).

* principal investigator

Service

  1. SoLS Events Committee, (2007 - present)
  2. SoLS Safety Committee, (2007 - present)
  3. Alpha Phi Omega Service Fraternity, Faculty Advisor (2007 - present)
  4. Cold Spring Harbor Laboratories Meetings and Courses, Course Director (2009)
  5. Cold Spring Harbor Laboratories Meetings and Courses, Course Director (2008)